Pure-Pass GLC Well Plates and Sealing Mats | Trajan

High-throughput clinical laboratories depend on continuous, reliable automation to deliver fast turnaround times. However, when analyzing hydrophobic analytes, glass surfaces are essential for ensuring accurate, reproducible results.

Until now, using glass in automated workflows has relied on workarounds - such as glass vials or inserts in polypropylene plates. These setups can increase the risk of alignment issues during automated liquid handling, leading to interrupted or failed runs. The result: re-runs, downtime, and lost productivity—especially during unattended overnight operations.

To address these challenges, Trajan developed the Pure-Pass™ GLC™ plate. Featuring a glass-like coating in a standard plate format, it delivers the performance of glass while maintaining full compatibility with automated workflows - enabling more reliable automation, fewer interruptions and higher productivity. Pure-Pass GLC plates, give you the confidence to run overnight.

No glass vials. No plate inserts.

No interruptions – just higher productivity.

Constant bore explained

A constant bore emitter maintains a uniform internal diameter right to the tip, eliminating abrupt constrictions that can disrupt fluid dynamics. This streamlined design promotes smooth, laminar flow, minimizes turbulence, and reduces sites for particle buildup — significantly lowering the risk of clogging.

The outcome is fewer interruptions, fewer reruns, and consistently higher throughput for demanding workflows.

"Trajan’s Pure-Pass GLC well plates have transformed our automated workflow for challenging samples. By eliminating plate-to-vial transfers, we streamlined automation and reduced handling steps. Removing glass vials also minimized misalignments and prevented needle damage, cutting instrument downtime and improving lab productivity"

Wanzhu ZhaoiC42 Toxicology, University of Colorado

Commitment to quality

Quality manufacturing starts with control at every stage — from raw material selection and precision production to rigorous quality testing. By combining advanced process control with consistent manufacturing standards, Trajan delivers reliable, high-performance well plates designed for demanding analytical workflows. Pure-Pass GLC plates are manufactured in a controlled cleanroom environment, under a quality management system certified to ISO 9001.

Make the right choice

Whether you’re using 96 or 384 well formats, Pure-Pass GLC provides multiple volume options to fit seamlessly into your workflow. Engineered from low leachable polypropylene with advanced GLC technology, it meets ANSI/SLAS standards for reliable compatibility with automated platforms.

Made from low leachable silicone to protect sample integrity, Pure-Pass sealing mats deliver effective sealing performance that minimizes evaporation and prevents contamination. A plasma coated, non stick surface ensures clean, effortless handling.

FAQs

Will the plate be more fragile/more prone to breakage if it contains glass?

No. Pure-Pass GLC well plates retain simplicity of use and sturdiness of the polypropylene material. Standard precaution and care should be applied, but the glass-like coating does not require any special handling.

Do Pure-Pass GLC well plates come with the barcode?

Yes. A unique barcode is applied to each well plate to help sample tracking and management.

Is the glass-like coating clear at the bottom of the well for imaging/biology applications?

Pure-Pass GLC well plates are translucent, but they are not designed for imaging and biology applications.

Pure-Pass GLC well plates are used for sample storage and processing for chromatography and analytical applications in clinical monitoring, pharma, biopharma, food and environmental applications.

How do Pure-Pass GLC well plates improve automated workflows?

Pure-Pass GLC well plates are particularly useful for high-throughput workflows where polypropylene plates are not suitable. GLC glass-like surface technology ensures minimal interaction with samples.

Unlike glass vials or glass inserts, ANSI/SLAS compliance of the Pure-Pass GLC well plates enables standardize robotic handling and liquid transfers reducing manual intervention. Result is a consumable product that integrates seamlessly with your automated workflow and consistent results.

What chemicals are the Pure-Pass GLC well plate resistant to?

The Pure-Pass GLC well plates are generally suitable for use with aqueous and acidic aqueous/solvent mixtures, such as utilized in reverse phase LC-MS applications where hydrophobic analytes may bind to untreated polypropylene surfaces.

Plates are generally suitable with solvents that do not swell polypropylene, but application specific validations is recommended for use with solvents.

What is the difference between the Pure-Pass sealing mats and regular silicone-based sealing mats?

Pure-Pass sealing mats offers excellent chemical resistance of silicone, but they are specially processed to reduce sample contamination by low bleed extractables. Plasma coating reduces natural tackiness of silicone easier for handling and additional protection from contaminants adhering to silicone. Each mat has an alphanumeric grid reference for sample tracking. Result is lower risk of contamination and easier handling.

How do I choose between slit vs. non pre-slit Pure-Pass sealing mats?

Pure-Pass sealing mats provide effective sealing with 96-well and 384-well plates. The slit version enhances sample recovery by reducing vacuum formation. We recommend using the slit version for small volumes and sensitive analysis.